Improvements in Ability to Detect Undiagnosed Diabetes by Using Information on Family History Among Adults in the United States

Improvements in Ability to Detect Undiagnosed Diabetes by Using Information on Family History Among Adults in the United States

Diabetes: Genomics & Family History

CDC information: More than 29 million Americans have diabetes; 1 in 4 doesn’t know

CDC study:  Using family history improves ability to detect undiagnosed diabetes among adults in the US.

If you have a mom, dad, brother or sister with type 2 diabetes you have a greater chance of getting the disease, the National Diabetes Education Program

CDC Diabetes Public Health Resource

Susceptibility to type 2 diabetes mellitus—from genes to prevention. 
Marie-France Hivert et al. Nature Reviews Endocrinology (2014)

CDC information: Prediabetes: Am I at risk?

Did you know? More than 3300 genes have been reported with risk of type 2 diabetes and its outcomes, including more than 150 genomewide association studies. To find out more, visit the HuGE Navigator

Check out genetic disorders and tests associated with diabetes at the NIH Genetic Testing Registry

Gene-lifestyle interaction and type 2 diabetes: The EPIC InterAct case-cohort study.

Recent studies

Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population. 
The SIGMA Type 2 Diabetes Consortium JAMA. 2014;311(22):2305-2314.

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Ida Moltke et al. Nature, June 2014